Abstract:
One of the major problems observed in veterinary practice is articular cartilage injuries in animals. In terms of
agriculture, it leads to their culling from the herd, even if they are highly productive animals. With companion animals,
owners usually have to decide between euthanasia or long-term sometimes lifelong treatment of the injury by a
veterinarian. The use of mesenchymal stem cells (MSCs) for the treatment of cartilage injury in veterinary medicine is
based on the good results observed in preclinical studies, where large animals have been used as experimental models
to study the regenerative activity of MSCs. According to the literature, MSCs in veterinary medicine have been used
to treat cartilage injury of dogs and horses, whereas sheep and goats are generally models for reproducing the disease
in preclinical experimental studies.
