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Study of the interaction of lovastatin with a transition group metal - gadolinium in solution using NMR spectroscopy

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dc.contributor Казанский федеральный университет
dc.contributor.author Islamov Timur Rafisovich
dc.contributor.author Aganova Oksana Vartanovna
dc.contributor.author Julmetov Ajdar Rafailevich
dc.contributor.author Klochkov Vladimir Vasilevich
dc.date.accessioned 2024-10-07T12:46:54Z
dc.date.available 2024-10-07T12:46:54Z
dc.date.issued 2024
dc.identifier.citation Study of the interaction of lovastatin with a transition group metal-gadolinium in solution using NMR spectroscopy / T.R. Islamov, O.V. Aganova, A.R. Julmetov, V.V. Klochkov // Magnetic resonance-current and future perspectives (EPR - 80): book of abstract of the international conferences. - Kazan, 2024. - P. 234-235.
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/184886
dc.description.abstract Modification of biologically active compounds through the use of metal complexes is one of the promising directions in the development of drugs that must have certain previously known properties. Statins, being the most effective way to relieve atherosclerosis, have a wide range of side effects, such as myositis, increased production of liver enzymes. Studying the interaction of statins with transition group metals will help clarify ways to create a stable metal complex and subsequent studies on changes in pharmacokinetics. During the work, the type of interaction between lovastatin and gadolinium was determined as rapid exchange.
dc.language.iso en
dc.relation.ispartofseries Magnetic resonance - current and future perspectives (EPR - 80) : book of abstract of the international conferences.
dc.rights открытый доступ
dc.subject statin
dc.subject NMR spectroscopy
dc.subject.other Физика
dc.title Study of the interaction of lovastatin with a transition group metal - gadolinium in solution using NMR spectroscopy
dc.type Article
dc.contributor.org Институт физики
dc.description.pages 239-240
dc.pub-id 304271


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