Application of Mesenchymal Stem Cells Derived Artificial Microvesicles for the Treatment of Canine Skin Wound

Abstract

Large full-thickness skin defects represent a serious veterinary problem. We have developed a novel therapy for canine skin wounds using extracellular vesicles derived from mesenchymal stem cells. Successful wound healing was observed with a positive clinical outcome for the canine patient. The extracellular vesicles stimulated a regenerative process in the skin in comparison to classic therapy. This represents a novel and innovative method for exploring would healing and disorders requiring regeneration.