The Influence of the Xymedon Сonjugate with l-Methionine on the Regeneration of Schmidtea mediterranea Planarians

Abstract

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. The effect of the Xymedon conjugate with methionine on blastema regeneration in Schmidtea mediterranea planarians was investigated. It was established that the preparation has low toxicity towards planarians, which is evidenced by its CL50 values (lethal concentration). The results of the vital computer morphometry and flow cytofluorometry confirm that Xymedon with methionine induces regeneration at high concentrations only: 0.01 g/100 mL, 0.05 g/100 mL, and 0.1 mg/100 mL. Low concentrations of the preparation have no influence on blastema regeneration in planarians.