Approximation of the Dependency of Trace Elements Concentrations in Internal Media upon their Contents in Environment Objects

Abstract

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Models that demonstrate the dependency of a trace element content in the internal milieu of an organism upon that in external media objects of the environment were developed to identify dominant factors in ecology-mediated microelement imbalance in a human body. Based on the sets of experimental data obtained on trace element concentrations in the internal milieu (fluids) of a human body (blood) and accumulating media (hair), external fluids (drinking water), and deposit media (soil and snow cover), the degree of approximation of dependencies captured with different models was estimated, with the most adequate ones chosen. Linear, cubic, logistic, sigmoidal, parabolic functions, a polynomial of the fourth and fifth degrees, the Nelder–Mead optimization algorithm, and a Boltzmann function were applied to evaluate the approximation degree by different models. The selection of internal and external media demonstrating the best approximation results is justified.