Synthesis of Hybrid Pharmacophores Based on Adducts of N-Sulfinylaniline and Norbornadiene

Abstract

© 2018, Pleiades Publishing, Ltd. Acylation of benzothiazinesulfonamides obtained by the oxidation of N-sulfinylaniline and norbornadiene adducts with acid chlorides and carboxylic anhydrides led to the formation of N-acylated sulfonamide hybrid pharmacophores. Molecular and crystal structure of the acylated products was established by X-ray diffraction method.