dc.contributor.author |
Zverev A. |
|
dc.contributor.author |
Anikina T. |
|
dc.contributor.author |
Iskakov N. |
|
dc.contributor.author |
Zefirov A. |
|
dc.contributor.author |
Zefirov T. |
|
dc.date.accessioned |
2019-01-22T20:31:51Z |
|
dc.date.available |
2019-01-22T20:31:51Z |
|
dc.date.issued |
2018 |
|
dc.identifier.issn |
0007-4888 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/147582 |
|
dc.description.abstract |
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. We studied the effect of neuropeptide Y in concentrations of 10—8-10—6 M on electrical activity of adult rat right atrial cardiomyocytes with preserved spontaneous activity. Neuropeptide Y was found to modulate the amplitude-time parameters of action potential: in concentrations of 10—7 and 10—6 M it reduced the membrane potential, increased the amplitude of action potential and duration of the repolarization phase, and reduced the frequency of action potential generation. In concentration of 10—6 M, neuropeptide Y produced stronger effect on the analyzed parameters, while in concentration of 10—8 M it produced no significant changes. |
|
dc.relation.ispartofseries |
Bulletin of Experimental Biology and Medicine |
|
dc.subject |
action potential |
|
dc.subject |
cardiomyocytes |
|
dc.subject |
membrane potential |
|
dc.subject |
neuropeptide Y |
|
dc.subject |
rat |
|
dc.title |
Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
5 |
|
dc.relation.ispartofseries-volume |
165 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
610 |
|
dc.source.id |
SCOPUS00074888-2018-165-5-SID85053518316 |
|