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dc.contributor.author | Zverev A. | |
dc.contributor.author | Anikina T. | |
dc.contributor.author | Iskakov N. | |
dc.contributor.author | Zefirov A. | |
dc.contributor.author | Zefirov T. | |
dc.date.accessioned | 2019-01-22T20:31:51Z | |
dc.date.available | 2019-01-22T20:31:51Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 0007-4888 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/147582 | |
dc.description.abstract | © 2018, Springer Science+Business Media, LLC, part of Springer Nature. We studied the effect of neuropeptide Y in concentrations of 10—8-10—6 M on electrical activity of adult rat right atrial cardiomyocytes with preserved spontaneous activity. Neuropeptide Y was found to modulate the amplitude-time parameters of action potential: in concentrations of 10—7 and 10—6 M it reduced the membrane potential, increased the amplitude of action potential and duration of the repolarization phase, and reduced the frequency of action potential generation. In concentration of 10—6 M, neuropeptide Y produced stronger effect on the analyzed parameters, while in concentration of 10—8 M it produced no significant changes. | |
dc.relation.ispartofseries | Bulletin of Experimental Biology and Medicine | |
dc.subject | action potential | |
dc.subject | cardiomyocytes | |
dc.subject | membrane potential | |
dc.subject | neuropeptide Y | |
dc.subject | rat | |
dc.title | Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart | |
dc.type | Article | |
dc.relation.ispartofseries-issue | 5 | |
dc.relation.ispartofseries-volume | 165 | |
dc.collection | Публикации сотрудников КФУ | |
dc.relation.startpage | 610 | |
dc.source.id | SCOPUS00074888-2018-165-5-SID85053518316 |