Synthesis of p-tert-butylthiacalix[4]arene derivatives with 1-aminobis(methylenephosphonic acid) fragments by Moedritzer-Irani reaction

Abstract

© 2016 Taylor & Francis Group, LLC.Novel tetra-substituted p-tert-butylthicalix[4]arene derivatives with 1-aminobis(methylenephosphonic) acid fragments at the lower rim in 1,3-alternate conformation were synthesized byMoedritzer-Irani reaction with good yields. It was shown that thiacalixarene derivatives containing both amino and hydroxyl groups at the lower rim did not undergo Moedritzer-Irani reaction.