Structure of amyloid-beta peptides in a complex with model membranes

Abstract

Structures of amyloid-beta peptides Aβ<inf>1-40</inf>, Aβ<inf>10-35</inf>, Aβ<inf>13-23</inf> and Aβ<inf>16-22</inf> in a complex with model membranes in solution were obtained on the analysis of NMR experimental data. It has been established that the process of peptide-micelle complex formation occurs through the amino acid residues L17, F19, F20 and G29-M35.