Amperometric Detection of Allopurinol in Flow-Injection Analysis on Electrodes Modified by Carbon Nanotubes and Mixed-Valence Ruthenium and Iridium Oxides

Abstract

© 2014, Springer Science+Business Media New York. Mixed-valence oxides of ruthenium (RuO<inf>x</inf>) and iridium (IrO<inf>x</inf>) and a composite based on them (IrO<inf>x</inf>—RuO<inf>x</inf>) exhibited catalytic activity for allopurinol oxidation when electrodeposited on the surfaces of unmodified glassy-carbon electrodes and those modified with functionalized single-walled carbon nanotubes (SWCNT). The greatest catalytic effect was observed on the electrode modified with composite IrO<inf>x</inf>—RuO<inf>x</inf>—SWCNT. A flow-injection method for amperometric detection of allopurinol at the modified electrode was developed. The analytical signal was linearly dependent on allopurinol concentration in the range 1 × 10^{– 6} – 5 ×10⁻³ M.