Synthesis of carboxylate phosphabetaines from 3-(diphenylphosphino)propanoic acid and unsaturated monocarboxylic acids

Abstract

© 2015 Pleiades Publishing, Ltd. Stable dicarboxylate phosphabetaines were synthesized by the phosphorylation of a series of unsaturated monocarboxylic acids (acrylic, crotonic, methacrylic, and cinnamic) with 3-(diphenylphosphino)-propanoic acid. The structure of the products was assessed by chemical, physical, and physicochemical methods. Alkylation of 3-(diphenylphosphino)propanoic acid with methyl iodide was studied for the first time to show that the reaction proceeds smoothly and yields the corresponding quaternary phosphonium salt.