The reaction of 2-ethoxy-3-phenylbenzo[ d ]-1,3, 2-oxazaphosphorin-6-one with α-ketocarboxylic acid esters: Synthesis of benzo[ d ]-1,3,2-oxazaphosphepine derivatives

Abstract

The reactions of 2-ethoxy-3-phenylbenzo[d]-1,3,2-oxazaphosphorin-6-one with R-carbonylcarboxylic acids ethyl esters (R = CF3, Ph, and Me) lead to the formation of seven-membered heterocycles, 2-ethoxy-9-ethoxycarbonyl-2,8- dioxo-3-phenyl-9-R-benzo[d]-1,3,2-oxazaphosphepines. © 2013 Copyright Taylor and Francis Group, LLC.