Microwave-assisted Alkylation of p-tert-butylcalix[4]arene Lower Rim: The Effect of Alkyl Halides

Abstract

Alkylation of p-tert-butylcalix[4]arenes with alkyl bromides or iodides under microwave irradiation affords mostly the corresponding distal disubstituted ethers, whereas in case of alkyl chlorides reasonable yields of monoethers were achieved. © 2013 Mendeleev Communications. All rights reserved.