Partition constants of α-aminophosphonates in two-phase aqueous-organic solvent systems

Abstract

Two-phase potentiometric titration was used to determine partition constants for a series of α-aminophosphonates (RO)2P(O)CH 2NR1R2 [R = Alk (C2-C5), R1, R2 = Me, Et, (CH2)5] between water and organic solvents, such as chloroform, carbon tetrachloride, toluene, octane, n-octanol, nitrobenzene, o-xylene, and cyclohexane. Correlations between the partition constants and the number of carbon atoms in substrate molecules were obtained. Solvent effects on partition constants were discussed, and solution parameters of α-aminophosphonates were calculated. ©2004 MAIK "Nauka/Interperiodica".