Dimethyl dichloromalonate as a new synthetic equivalent of methyl dichloroacetate in the Darzens condensation

Abstract

Dimethyl dichloromalonate reacts with aldehydes in the presence of sodium methoxide to form α-chloropyruvates, α-chloroglycidates, or α,α-dichlorohydrins, depending on the nature of the aldehyde. © 1995, Plenum Publishing Corporation. All rights reserved.