An enzyme amperometric sensor for toxicant determination

Abstract

An enzyme sensor with amperometric recording of the analytic signal for determination of a number of cholinesterase (ChE) inhibitors (P-, Cl-containing pesticides, heavy metals) has been developed. It consists of a mercury film-covered silver electrode and ChE immobilized in the nitrocellulose film in the presence of glutaraldehyde. It is shown that the enzyme electrode can be used as a component of an enzyme reactor for the determination of ChE inhibitors and activators under flow conditions. © 1991.