Study of the multipositional conformational exchange in 2,2-dimethyl-1,3-dithiepin and its 5,6-benz analog by two-dimensional NMR spectroscopy

Abstract

Two-dimensional NMR spectroscopy was used to establish that the chair ⇄ chair-inversion process in 2,2-dimethyl-1,3-dithiepin and its 5,6-benz derivative is a function of transitions between intermediate boat and twist structures, while the role of direct chair ⇄ chair transitions is small. © 1990 Plenum Publishing Corporation.