Synthesis of the β isomers of 2,4,6-trisubstituted 1,3,5-trithianes

Abstract

The condensation of bis(α-hydroxy-β,β,β-trichloroethyl) sulfide with aldehydes under acid catalysis conditions gives 2,4,6-trisubstituted 1,3,5-trithianes. The latter are realized only in the thermodynamically more favorable β forms. © 1977 Plenum Publishing Corporation.