Browsing Публикации сотрудников КФУ Scopus by Author "Wu S."

Now showing items 1-3 of 3

ARID1A spatially partitions interphase chromosomes

Wu S.; Fatkhutdinov N.; Rosin L.; Luppino J.; Iwasaki O.; Tanizawa H.; Tang H.; Kossenkov A.; Gardini A.; Noma K.; Speicher D.; Joyce E.; Zhang R. (2019)

© 2019 by the Authors. ARID1A, a subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex, localizes to both promoters and enhancers to influence transcription. However, the role of ARID1A in ...
N<sup>6</sup>-methylation of adenosine of FZD10 mRNA contributes to PARP inhibitor resistance

Fukumoto T.; Zhu H.; Nacarelli T.; Karakashev S.; Fatkhutdinov N.; Wu S.; Liu P.; Kossenkov A.; Showe L.; Jean S.; Zhang L.; Zhang R. (2019)

© 2019 American Association for Cancer Research. Despite the high initial response rates to PARP inhibitors (PARPi) in BRCA-mutated epithelial ovarian cancers (EOC), PARPi resistance remains a major challenge. Chemical ...
SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

Wu S.; Fatkhutdinov N.; Fukumoto T.; Bitler B.; Park P.; Kossenkov A.; Trizzino M.; Tang H.; Zhang L.; Gardini A.; Speicher D.; Zhang R. (2018)

© 2018, The Author(s). Inactivation of the subunits of SWI/SNF complex such as ARID1A is synthetically lethal with inhibition of EZH2 activity. However, mechanisms of de novo resistance to EZH2 inhibitors in cancers with ...

Now showing items 1-3 of 3

Search DSpace