Показать сокращенную информацию
dc.contributor.author | Saal Christoph | |
dc.contributor.author | Nair Anita | |
dc.date.accessioned | 2024-01-26T21:46:04Z | |
dc.date.available | 2024-01-26T21:46:04Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Solubility in pharmaceutical chemistry - 1 online resource - URL: https://libweb.kpfu.ru/ebsco/pdf/2333427.pdf | |
dc.identifier.isbn | 3110558882 | |
dc.identifier.isbn | 9783110559835 | |
dc.identifier.isbn | 3110559838 | |
dc.identifier.isbn | 9783110558883 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/179040 | |
dc.description | In English. | |
dc.description.abstract | This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book. | |
dc.description.tableofcontents | Elder, David -- Bauer-Brandl, Annette / Brandl, Martin -- McDonagh, James L. / Mitchell, John Bo / Palmer, David S / Skyner, Rachael E. -- Faller, Bernard / Desrayaud, Sandrine / Berghausen, Joerg / Laisney, Marc / Dodd, Stephanie -- Reppas, Christos / Vertzoni, Maria -- Dressman, Jennifer -- Saal, Christoph / Valko, Klara -- Holm, René -- Saal, Christoph -- Beckmann, Wolfgang -- Elder, David -- Frontmatter -- Contents -- List of contributors -- 1. Solubility -- definition and basic physicochemical considerations / 2. Solubility and supersaturation / 3. In Silico methods to predict solubility / 4. How solubility influences bioavailability / 5. Estimation of intraluminal drug solubility / 6. Biorelevant media / 7. The role of solubility to optimize drug substances -- a medicinal chemistry perspective / 8. The role of solubility in optimizing drug products -- a pharmaceutical development perspective / 9. The relevance of solid-state forms for solubility / 10. Solubility and phase behaviour from a drug substance manufacturing perspective / 11. Biowaivers / List of Abbreviations -- Index | |
dc.language | English | |
dc.language.iso | en | |
dc.subject.other | Drugs -- Solubility. | |
dc.subject.other | Pharmaceutical chemistry. | |
dc.subject.other | Solubility. | |
dc.subject.other | Drugs. | |
dc.subject.other | Solubility | |
dc.subject.other | Chemistry, Pharmaceutical | |
dc.subject.other | Pharmaceutical Preparations | |
dc.subject.other | Médicaments -- Solubilité. | |
dc.subject.other | Chimie pharmaceutique. | |
dc.subject.other | Solubilité. | |
dc.subject.other | Médicaments. | |
dc.subject.other | solubility. | |
dc.subject.other | MEDICAL -- Pharmacology. | |
dc.subject.other | Drugs -- Solubility | |
dc.subject.other | Pharmaceutical chemistry | |
dc.subject.other | Electronic books. | |
dc.title | Solubility in pharmaceutical chemistry/ edited by Christoph Saal, Anita Nair. | |
dc.type | Book | |
dc.description.pages | 1 online resource | |
dc.collection | Электронно-библиотечные системы | |
dc.source.id | EN05CEBSCO05C340306 |