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Pre-motor versus motor cerebral cortex neuromodulation for chronic neuropathic pain

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dc.contributor.author Lavrov I.
dc.contributor.author Latypov T.
dc.contributor.author Mukhametova E.
dc.contributor.author Lundstrom B.
dc.contributor.author Sandroni P.
dc.contributor.author Lee K.
dc.contributor.author Klassen B.
dc.contributor.author Stead M.
dc.date.accessioned 2022-02-09T20:43:47Z
dc.date.available 2022-02-09T20:43:47Z
dc.date.issued 2021
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/169868
dc.description.abstract Electrical stimulation of the cerebral cortex (ESCC) has been used to treat intractable neuropathic pain for nearly two decades, however, no standardized approach for this technique has been developed. In order to optimize targeting and validate the effect of ESCC before placing the permanent grid, we introduced initial assessment with trial stimulation, using a temporary grid of subdural electrodes. In this retrospective study we evaluate the role of electrode location on cerebral cortex in control of neuropathic pain and the role of trial stimulation in target-optimization for ESCC. Location of the temporary grid electrodes and location of permanent electrodes were evaluated in correlation with the long-term efficacy of ESCC. The results of this study demonstrate that the long-term effect of subdural pre-motor cortex stimulation is at least the same or higher compare to effect of subdural motor or combined pre-motor and motor cortex stimulation. These results also demonstrate that the initial trial stimulation helps to optimize permanent electrode positions in relation to the optimal functional target that is critical in cases when brain shift is expected. Proposed methodology and novel results open a new direction for development of neuromodulation techniques to control chronic neuropathic pain.
dc.title Pre-motor versus motor cerebral cortex neuromodulation for chronic neuropathic pain
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 11
dc.collection Публикации сотрудников КФУ
dc.source.id SCOPUS-2021-11-1-SID85108174436


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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