dc.contributor.author |
Bukharov S.V. |
|
dc.contributor.author |
Burilov A.R. |
|
dc.contributor.author |
Tagasheva R.G. |
|
dc.contributor.author |
Nugumanova G.N. |
|
dc.contributor.author |
Nikitina E.V. |
|
dc.contributor.author |
Mukmeneva N.A. |
|
dc.date.accessioned |
2022-02-09T20:36:06Z |
|
dc.date.available |
2022-02-09T20:36:06Z |
|
dc.date.issued |
2021 |
|
dc.identifier.issn |
1070-4280 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/169315 |
|
dc.description.abstract |
Abstract: New sulfanilamide derivatives containing sterically hindered phenol fragments have been synthesized via modification of the amino group by reaction with 3,5-di-tert-butyl-4-hydroxybenzyl acetate and diazotization followed by diazo coupling with 2,4-di-tert-butylphenol. 4-Aminobenzenesulfonamide derivatives at the sulfonamide group have been obtained by converting acetyl-protected 4-aminobenzenesulfonyl chloride to the corresponding sulfonohydrazide and reacting the latter with 3,5-di-tert-butyl-4-hydroxybenzyl acetate, sterically hindered hydroxybenzaldehydes, and N-(3,5-di-tert-butyl-4-hydroxybenzyl)isatin. Modification of sulfanilamide with sterically hindered phenol fragments significantly increased antibacterial activity. |
|
dc.relation.ispartofseries |
Russian Journal of Organic Chemistry |
|
dc.subject |
antibacterial activity |
|
dc.subject |
sterically hindered phenols |
|
dc.subject |
sulfanilamides |
|
dc.title |
Synthesis and Antibacterial Activity of Sulfanilamides Containing Sterically Hindered Phenol Fragments |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
10 |
|
dc.relation.ispartofseries-volume |
57 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
1621 |
|
dc.source.id |
SCOPUS10704280-2021-57-10-SID85120793068 |
|