Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group

dc.contributor.author	Tsepaeva O.V.
dc.contributor.author	Nemtarev A.V.
dc.contributor.author	Grigor’eva L.R.
dc.contributor.author	Mironov V.F.
dc.date.accessioned	2022-02-09T20:35:59Z
dc.date.available	2022-02-09T20:35:59Z
dc.date.issued	2021
dc.identifier.issn	1066-5285
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/169300
dc.description.abstract	A convenient method for the synthesis of C(28)-linker derivatives of triterpenoids containing a phosphonate group is presented. The method is based on the reaction of triterpenic acids (using betulinic acid as an example) with O, O-dialkyl-ω-bromoalkane phosphonates in DMF in the presence of K2CO3. The target phosphonates are synthesized in a yield of about 80%. The structures and compositions of the synthesized compounds were confirmed by NMR spectroscopy, IR spectroscopy, and elemental analysis.
dc.relation.ispartofseries	Russian Chemical Bulletin
dc.subject	betulinic acid
dc.subject	esters
dc.subject	phosphonates
dc.subject	triterpenoids
dc.title	Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group
dc.type	Article
dc.relation.ispartofseries-issue	1
dc.relation.ispartofseries-volume	70
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	179
dc.source.id	SCOPUS10665285-2021-70-1-SID85101567072

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Публикации сотрудников КФУ Scopus [24551]
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