dc.contributor.author |
Beilinson R.M. |
|
dc.contributor.author |
Yavisheva A.A. |
|
dc.contributor.author |
Medyantseva E.P. |
|
dc.contributor.author |
Budnikov H.C. |
|
dc.date.accessioned |
2022-02-09T20:35:27Z |
|
dc.date.available |
2022-02-09T20:35:27Z |
|
dc.date.issued |
2021 |
|
dc.identifier.issn |
1061-9348 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/169243 |
|
dc.description.abstract |
Abstract: We developed amperometric biosensors for the determination of diclofenac based on screen-printed platinum electrodes modified by carbon nanotubes in chitosan, fullerene C60 in Boltorn H20, gold nanoparticles in chitosan, and immobilized tyrosinase enzyme. Diclofenac is a reversible tyrosinase inhibitor, which enables its determination using appropriate biosensors modified by nanomaterials in the concentration range from 10 pM to 1 μM with cl = 5 pM. Kinetic studies of the reaction of the enzymatic conversion of phenol showed that, in the presence of diclofenac, noncompetitive inhibition is observed on a tyrosinase biosensor. We tested the procedures for the determination of diclofenac in cow’s milk using the proposed biosensors. |
|
dc.relation.ispartofseries |
Journal of Analytical Chemistry |
|
dc.subject |
carbon nanotubes |
|
dc.subject |
diclofenac |
|
dc.subject |
fullerene C 60 |
|
dc.subject |
gold nanoparticles |
|
dc.subject |
tyrosinase biosensor |
|
dc.title |
Amperometric Tyrosinase Biosensors Modified by Nanomaterials of Different Nature for Determining Diclofenac |
|
dc.type |
Article |
|
dc.relation.ispartofseries-issue |
5 |
|
dc.relation.ispartofseries-volume |
76 |
|
dc.collection |
Публикации сотрудников КФУ |
|
dc.relation.startpage |
653 |
|
dc.source.id |
SCOPUS10619348-2021-76-5-SID85105943555 |
|