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dc.contributor.author | Beilinson R.M. | |
dc.contributor.author | Yavisheva A.A. | |
dc.contributor.author | Medyantseva E.P. | |
dc.contributor.author | Budnikov H.C. | |
dc.date.accessioned | 2022-02-09T20:35:27Z | |
dc.date.available | 2022-02-09T20:35:27Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1061-9348 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/169243 | |
dc.description.abstract | Abstract: We developed amperometric biosensors for the determination of diclofenac based on screen-printed platinum electrodes modified by carbon nanotubes in chitosan, fullerene C60 in Boltorn H20, gold nanoparticles in chitosan, and immobilized tyrosinase enzyme. Diclofenac is a reversible tyrosinase inhibitor, which enables its determination using appropriate biosensors modified by nanomaterials in the concentration range from 10 pM to 1 μM with cl = 5 pM. Kinetic studies of the reaction of the enzymatic conversion of phenol showed that, in the presence of diclofenac, noncompetitive inhibition is observed on a tyrosinase biosensor. We tested the procedures for the determination of diclofenac in cow’s milk using the proposed biosensors. | |
dc.relation.ispartofseries | Journal of Analytical Chemistry | |
dc.subject | carbon nanotubes | |
dc.subject | diclofenac | |
dc.subject | fullerene C 60 | |
dc.subject | gold nanoparticles | |
dc.subject | tyrosinase biosensor | |
dc.title | Amperometric Tyrosinase Biosensors Modified by Nanomaterials of Different Nature for Determining Diclofenac | |
dc.type | Article | |
dc.relation.ispartofseries-issue | 5 | |
dc.relation.ispartofseries-volume | 76 | |
dc.collection | Публикации сотрудников КФУ | |
dc.relation.startpage | 653 | |
dc.source.id | SCOPUS10619348-2021-76-5-SID85105943555 |