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Antimicrobial drug resistance mechanisms among Mollicutes

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dc.contributor.author Chernova O.A.
dc.contributor.author Chernov V.M.
dc.contributor.author Mouzykantov A.A.
dc.contributor.author Baranova N.B.
dc.contributor.author Edelstein I.A.
dc.contributor.author Aminov R.I.
dc.date.accessioned 2022-02-09T20:34:29Z
dc.date.available 2022-02-09T20:34:29Z
dc.date.issued 2021
dc.identifier.issn 0924-8579
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/169124
dc.description.abstract Representatives of the Mollicutes class are the smallest, wall-less bacteria capable of independent reproduction. They are widespread in nature, most are commensals, and some are pathogens of humans, animals and plants. They are also the main contaminants of cell cultures and vaccine preparations. Despite limited biosynthetic capabilities, they are highly adaptable and capable of surviving under various stress and extreme conditions, including antimicrobial selective pressure. This review describes current understanding of antibiotic resistance (ABR) mechanisms in Mollicutes. Protective mechanisms in these bacteria include point mutations, which may include non-target genes, and unique gene exchange mechanisms, contributing to transfer of ABR genes. Better understanding of the mechanisms of emergence and dissemination of ABR in Mollicutes is crucial to control these hypermutable bacteria and prevent the occurrence of highly ABR strains.
dc.relation.ispartofseries International Journal of Antimicrobial Agents
dc.subject Antibiotic resistance mechanisms
dc.subject Antibiotic targets
dc.subject Antibiotics
dc.subject Antimicrobials
dc.subject Horizontal gene transfer
dc.subject Mobile genetic elements
dc.subject Mollicutes
dc.subject Point mutations
dc.title Antimicrobial drug resistance mechanisms among Mollicutes
dc.type Review
dc.relation.ispartofseries-issue 2
dc.relation.ispartofseries-volume 57
dc.collection Публикации сотрудников КФУ
dc.source.id SCOPUS09248579-2021-57-2-SID85098960411


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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