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Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications

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dc.contributor.author Guseva G.
dc.contributor.author Antina E.
dc.contributor.author Berezin M.
dc.contributor.author Lisovskaya S.
dc.contributor.author Pavelyev R.
dc.contributor.author Kayumov A.
dc.contributor.author Lodochnikova O.
dc.contributor.author Islamov D.
dc.contributor.author Usachev K.
dc.contributor.author Boichuk S.
dc.contributor.author Nikitina L.
dc.date.accessioned 2021-02-25T20:56:12Z
dc.date.available 2021-02-25T20:56:12Z
dc.date.issued 2020
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/162717
dc.description.abstract © 2020 by the authors. This study focuses on the behavior of a new fluorescent marker for labeling individual biomolecules and staining cell organelles developed on a meso-substituted BODIPY platform. Boron(III) complex with meso-4-methoxycarbonylpropylsubstituted 3,3',5,5'-tetramethyl-2,20- dipyrromethene has been synthesized and identified via visible, UV-, NMR- and MS-spectra X-ray. The behavior of fluorophore in solutions has been studied with various experimental techniques. It has been found that luminophore exhibits a high quantum yield (almost ∼100-75%) in the blue-green region (513-520 nm) and has high photostability. In addition, biological analysis indicates that the fluorophore exhibits a tendency to effectively penetrate into cell membranes. On the other hand, the proposed BODIPY can be used to study the significant differences among a large number of pathogens of mycotic infections, as well as to visualize structural changes in the plasma membrane, which is necessary for the clearance of mammalian cells undergoing apoptotic cell death.
dc.subject Biomarker
dc.subject BODIPY
dc.subject Dipyrromethene
dc.subject Fluorophore
dc.subject Pathogenic microorganisms
dc.title Spectroscopic and in vitro investigations of boron(III) complex with meso-4-methoxycarbonylpropylsubstituted dipyrromethene for fluorescence bioimaging applications
dc.type Article
dc.relation.ispartofseries-issue 19
dc.relation.ispartofseries-volume 25
dc.collection Публикации сотрудников КФУ
dc.source.id SCOPUS-2020-25-19-SID85092559267


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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