The advantages and disadvantages of synthesizing of arylarsonic acids

Abstract

© 2020, Advanced Scientific Research. All rights reserved. In recent years, an interest in research in the field of arsenicorganic compounds has increased in connection with the development of anticarcinogenic drugs. In this regard, research in the field of the synthesis of arsenic derivatives is of great theoretical and practical interest. Arsenic, like its counterparts from the fifth group of the periodic system created by D. I. Mendeleev, is a biofunctional element. Unlike phosphorus and nitrogen, arsenic has more pronounced toxic properties. Inorganic compounds of trivalent arsenic, arsine AsH3 and its derivatives, for example, halides, oxides, sulfides and other compounds, are highly toxic. Along with this, there are low-toxic substances among the organic derivatives of pentavalent arsenic. Some of them, possessing certain therapeutic properties, are used in medicine, some substances are used in the agro-industrial sector, in various industries. This article provides a brief overview of methods for the synthesis of arylarsonic acids containing a specific set of substituents in the benzene ring. The advantages and disadvantages of the synthesis methods described in the literature are analyzed. The most practical version of the synthesis of these acids has been proposed, which has been improved and recommended for use.