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dc.contributor.author | Sedrakyan A.M. | |
dc.contributor.author | Ktsoyan Z.A. | |
dc.contributor.author | Arakelova K.A. | |
dc.contributor.author | Zakharyan M.K. | |
dc.contributor.author | Hovhannisyan A.I. | |
dc.contributor.author | Gevorgyan Z.U. | |
dc.contributor.author | Mnatsakanyan A.A. | |
dc.contributor.author | Kakabadze E.G. | |
dc.contributor.author | Makalatia K.B. | |
dc.contributor.author | Chanishvili N.A. | |
dc.contributor.author | Pirnay J.P. | |
dc.contributor.author | Arakelyan A.A. | |
dc.contributor.author | Aminov R.I. | |
dc.date.accessioned | 2021-02-25T20:55:06Z | |
dc.date.available | 2021-02-25T20:55:06Z | |
dc.date.issued | 2020 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/162617 | |
dc.description.abstract | © Copyright © 2020 Sedrakyan, Ktsoyan, Arakelova, Zakharyan, Hovhannisyan, Gevorgyan, Mnatsakanyan, Kakabadze, Makalatia, Chanishvili, Pirnay, Arakelyan and Aminov. A total of 291 non-duplicate isolates of non-typhoidal Salmonella (NTS) were collected from the fecal samples of patients with salmonellosis in Armenia and Georgia during 1996–2016. The isolates were tested for resistance to antimicrobials, including extended-spectrum β-lactamases (ESBL). The high prevalence of multidrug-resistance (MDR) and ESBL-producer phenotypes was detected among Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) isolates collected from patients in Armenia between 1996 and 2016. A total of 36 MDR NTS isolates were subjected to whole genome sequencing (WGS) to determine the genetic background of antimicrobial resistance (AMR) and mobile genetic elements. All ESBL-producing S. Typhimurium isolates belonged to the same sequence type (ST328). The ESBL-producer phenotype was associated with plasmid-encoded CTX-M-5 production. A range of other plasmids was associated with resistance to other antimicrobials, including the MDR phenotype. | |
dc.subject | antimicrobial resistance | |
dc.subject | antimicrobial resistance genes | |
dc.subject | extended-spectrum β-lactamases | |
dc.subject | non-typhoidal Salmonella | |
dc.subject | WGS | |
dc.title | Extended-Spectrum β-Lactamases in Human Isolates of Multidrug-Resistant Non-typhoidal Salmonella enterica | |
dc.type | Article | |
dc.relation.ispartofseries-volume | 11 | |
dc.collection | Публикации сотрудников КФУ | |
dc.source.id | SCOPUS-2020-11-SID85098980815 |