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Synthesis of Water-Soluble Polyammonium Thiacalix[4]arene Derivative and Its Interaction with Calf Thymus DNA

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dc.contributor.author Burilov V.A.
dc.contributor.author Mironova D.A.
dc.contributor.author Grygoriev I.A.
dc.contributor.author Valiyakhmetova A.M.
dc.contributor.author Solovieva S.E.
dc.contributor.author Antipin I.S.
dc.date.accessioned 2021-02-25T20:38:38Z
dc.date.available 2021-02-25T20:38:38Z
dc.date.issued 2020
dc.identifier.issn 1070-3632
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/162143
dc.description.abstract © 2020, Pleiades Publishing, Ltd. A water-soluble thiacalix[4]arene derivative containing four diethylenetriamine fragments in 1,3-alternate stereoisomeric form has been obtained for the first time. Using ethidium bromide, it has been found that the macrocycle can interact with calf thymus DNA. The macrocycle has been found to interact with DNA via groove binding. The presence of four diethylenetriamine fragments on the calixarene platform leads to multivalent interactions with DNA, resulting in an increase in the binding constant by two orders of magnitude compared to individual diethylenetriamine.
dc.relation.ispartofseries Russian Journal of General Chemistry
dc.subject calix[4]arene
dc.subject deoxyribonucleic acid
dc.subject ethidium bromide
dc.subject fluorimetry
dc.title Synthesis of Water-Soluble Polyammonium Thiacalix[4]arene Derivative and Its Interaction with Calf Thymus DNA
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 90
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 99
dc.source.id SCOPUS10703632-2020-90-1-SID85082754880


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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