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Hybrid Nanocomposites as Electrode Modifiers in Amperometric Immunosensors for the Determination of Amitriptyline

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dc.contributor.author Medyantseva E.P.
dc.contributor.author Brusnitsyn D.V.
dc.contributor.author Gazizullina E.R.
dc.contributor.author Varlamova R.M.
dc.contributor.author Konovalova O.A.
dc.contributor.author Budnikov H.C.
dc.date.accessioned 2021-02-25T20:37:07Z
dc.date.available 2021-02-25T20:37:07Z
dc.date.issued 2020
dc.identifier.issn 1061-9348
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/162042
dc.description.abstract © 2020, Pleiades Publishing, Ltd. Abstract: Various nanostructured materials (graphene, fullerene C60, carbon nanotubes, and cobalt nanoparticles as a label) are used as nanocomposites to modify the surface of primary signal converters (screen-printed graphite electrode) in the development of amperometric immunosensors for the determination of tricyclic antidepressant amitriptyline. The use of nanomaterials improved the analytical characteristics of the corresponding immunosensors. The range of working concentrations of the immunosensor is 1 × 10–9–1 × 10–4 M, the lower limit of the analytical range is at a level of 5 × 10–10 M. The binding constants of antigen–antibody immune complexes are determined. Immunosensors are tested in the control of contents of medicinal preparations in urine.
dc.relation.ispartofseries Journal of Analytical Chemistry
dc.subject amitriptyline
dc.subject antibodies
dc.subject carbon nanotubes
dc.subject cobalt nanoparticles
dc.subject fullerene
dc.subject immunosensor
dc.subject label
dc.subject reduced graphene oxide
dc.title Hybrid Nanocomposites as Electrode Modifiers in Amperometric Immunosensors for the Determination of Amitriptyline
dc.type Article
dc.relation.ispartofseries-issue 4
dc.relation.ispartofseries-volume 75
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 536
dc.source.id SCOPUS10619348-2020-75-4-SID85083369002


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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