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A comparative study of the effectiveness of regimens for the treatment of calicivirus infection in cats-a comparative study

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dc.contributor.author Kulenkova J.V.
dc.contributor.author Ravilov R.K.
dc.contributor.author Mingaleev D.N.
dc.contributor.author Efimova M.A.
dc.contributor.author Trubkin A.I.
dc.date.accessioned 2021-02-25T20:36:01Z
dc.date.available 2021-02-25T20:36:01Z
dc.date.issued 2020
dc.identifier.issn 0972-4036
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/161961
dc.description.abstract © 2020, Veterinary Practitioner. All rights reserved. Feline calicivirus (FCV) is a frequent pathogen in cats. In most cases, it causes mild, self-limited acute diseases of the oral cavity and the upper respiratory tract or chronic diseases of the oral cavity. In recent years, virulent strains of FCV have been registered that cause severe, systemic diseases in cats, with a high mortality rate, and are not preventable with modern vaccines. This study aims to evaluate the effectiveness of various methods for the treatment of calicivirus infection in cats. The research was conducted on 30 stray cats with calicivirus infection. The animals were divided into three groups. We developed several treatment regimens based on antibacterial drugs (clindamycin and amoxicillin), as well as immune modulators, such as Phosprenyl and Maxidin. Additionally, globulin Globfel-4 was administered to the animals of the third group. Clinical signs and general health condition were recorded daily during 14 days, and again on days 20 and 30. Feline calicivirus presence was tested by quantitative polymerase chain reaction (qPCR) on days 0, 10, and 30. It was found that the inclusion of a specific globulin in the complex therapy, namely Globfel-4, allows reducing the convalescence period and eliminating the pathogen.
dc.relation.ispartofseries Veterinary Practitioner
dc.subject FCV
dc.subject Feline calicivirus
dc.subject Immunomodulators
dc.subject Therapy
dc.title A comparative study of the effectiveness of regimens for the treatment of calicivirus infection in cats-a comparative study
dc.type Article
dc.relation.ispartofseries-issue 1
dc.relation.ispartofseries-volume 21
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 88
dc.source.id SCOPUS09724036-2020-21-1-SID85095120079

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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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