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Complete Genome Sequence of Lactobacillus hilgardii LMG 7934, Carrying the Gene Encoding for the Novel PII-Like Protein PotN

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dc.contributor.author Zhuravleva D.E.
dc.contributor.author Iskhakova Z.I.
dc.contributor.author Ozhegov G.D.
dc.contributor.author Gogoleva N.E.
dc.contributor.author Khusnutdinova D.R.
dc.contributor.author Shagimardanova E.I.
dc.contributor.author Forchhammer K.
dc.contributor.author Kayumov A.R.
dc.date.accessioned 2021-02-25T20:35:01Z
dc.date.available 2021-02-25T20:35:01Z
dc.date.issued 2020
dc.identifier.issn 0343-8651
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/161854
dc.description.abstract © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Lactic acid bacteria are widespread in various ecological niches with the excess of nutrients and have reduced capabilities to adapt to starvation. Among more than 280 Lactobacillus species known to the date, only five, including Lactobacillus hilgardii, carry in their genome the gene encoding for PII-like protein, one of the central regulators of cellular metabolism generally responding to energy- and carbon–nitrogen status in many free-living Bacteria, Archaea and in plant chloroplasts. In contrast to the classical PII encoding genes, in L. hilgardii genome the gene for PII homologue is located within the potABCD operon, encoding the ABC transporter for polyamines. Based on the unique genetic context and low sequence identity with genes of any other so-far characterized PII subfamilies, we termed this gene potN (Pot-protein, Nucleotide-binding). The second specific feature of L. hilgardii genome is that many genes encoding the proteins with similar function are present in two copies, while with low mutual identity. Thus, L. hilgardii LMG 7934 genome carries two genes of glutamine synthetase with 55% identity. One gene is located within classical glnRA operon with the gene of GlnR-like transcriptional regulator, while the second is monocistronic. Together with the relative large genome of L. hilgardii as compared to other Lactobacilli (2.771.862 bp vs ~ 2.2 Mbp in median), these data suggest significant re-arrangements of the genome and a wider range of adaptive capabilities of L. hilgardii in comparison to other bacteria of the genus Lactobacillus.
dc.relation.ispartofseries Current Microbiology
dc.title Complete Genome Sequence of Lactobacillus hilgardii LMG 7934, Carrying the Gene Encoding for the Novel PII-Like Protein PotN
dc.type Article
dc.relation.ispartofseries-issue 11
dc.relation.ispartofseries-volume 77
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 3538
dc.source.id SCOPUS03438651-2020-77-11-SID85089453375


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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