Inflammasomes as targets for adjuvants

dc.contributor.author	Ivanov K.
dc.contributor.author	Garanina E.
dc.contributor.author	Rizvanov A.
dc.contributor.author	Khaiboullina S.
dc.date.accessioned	2021-02-25T06:41:03Z
dc.date.available	2021-02-25T06:41:03Z
dc.date.issued	2020
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/161000
dc.description.abstract	© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Inflammasomes are an essential part of the innate immune system. They are necessary for the development of a healthy immune response against infectious diseases. Inflammasome activation leads to the secretion of pro-inflammatory cytokines such as IL-1β and IL-18, which stimulate the adaptive immune system. Inflammasomes activators can be used as adjuvants to provide and maintain the strength of the immune response. This review is focused on the mechanisms of action and the effects of adjuvants on inflammasomes. The therapeutic and prophylaxis significance of inflammasomes in infectious diseases is also discussed.
dc.subject	Adjuvants
dc.subject	Cytokines
dc.subject	Inflammasomes
dc.subject	Innate immunity
dc.subject	Vaccines
dc.title	Inflammasomes as targets for adjuvants
dc.type	Review
dc.relation.ispartofseries-issue	4
dc.relation.ispartofseries-volume	9
dc.collection	Публикации сотрудников КФУ
dc.source.id	SCOPUS-2020-9-4-SID85083048250

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.