- Главная
- →
- Научные публикации в Scopus
- →
- Публикации сотрудников КФУ Scopus
- →
- Просмотр элемента
JavaScript is disabled for your browser. Some features of this site may not work without it.
Показать сокращенную информацию
| dc.contributor.author | Shilkin E.S. | |
| dc.contributor.author | Boldinova E.O. | |
| dc.contributor.author | Stolyarenko A.D. | |
| dc.contributor.author | Goncharova R.I. | |
| dc.contributor.author | Chuprov-Netochin R.N. | |
| dc.contributor.author | Khairullin R.F. | |
| dc.contributor.author | Smal M.P. | |
| dc.contributor.author | Makarova A.V. | |
| dc.date.accessioned | 2021-02-24T20:31:57Z | |
| dc.date.available | 2021-02-24T20:31:57Z | |
| dc.date.issued | 2020 | |
| dc.identifier.issn | 0006-2979 | |
| dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/160736 | |
| dc.description.abstract | © 2020, Pleiades Publishing, Ltd. Abstract: Tens of thousands of DNA lesions are formed in mammalian cells each day. DNA translesion synthesis is the main mechanism of cell defense against unrepaired DNA lesions. DNA polymerases iota (Pol ι), eta (Pol η), kappa (Pol κ), and zeta (Pol ζ) have active sites that are less stringent toward the DNA template structure and efficiently incorporate nucleotides opposite DNA lesions. However, these polymerases display low accuracy of DNA synthesis and can introduce mutations in genomic DNA. Impaired functioning of these enzymes can lead to an increased risk of cancer. | |
| dc.relation.ispartofseries | Biochemistry (Moscow) | |
| dc.subject | carcinogenesis | |
| dc.subject | DNA damage | |
| dc.subject | mutagenesis | |
| dc.subject | translesion DNA synthesis | |
| dc.title | Translesion DNA Synthesis and Carcinogenesis | |
| dc.type | Review | |
| dc.relation.ispartofseries-issue | 4 | |
| dc.relation.ispartofseries-volume | 85 | |
| dc.collection | Публикации сотрудников КФУ | |
| dc.relation.startpage | 425 | |
| dc.source.id | SCOPUS00062979-2020-85-4-SID85083988575 |
Файлы в этом документе
Данный элемент включен в следующие коллекции
-
Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.