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dc.contributor.author | Shumatbaeva A. | |
dc.contributor.author | Morozova J. | |
dc.contributor.author | Shalaeva Y. | |
dc.contributor.author | Gubaidullin A. | |
dc.contributor.author | Saifina A. | |
dc.contributor.author | Syakaev V. | |
dc.contributor.author | Bazanova O. | |
dc.contributor.author | Sapunova A. | |
dc.contributor.author | Voloshina A. | |
dc.contributor.author | Nizameev I. | |
dc.contributor.author | Kadirov M. | |
dc.contributor.author | Konovalov A. | |
dc.date.accessioned | 2020-01-22T20:34:18Z | |
dc.date.available | 2020-01-22T20:34:18Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0927-7757 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/157951 | |
dc.description.abstract | © 2019 Elsevier B.V. The synthesis and study of self-association and encapsulation ability of new low toxic conjugate of tetraphenyleneoxypentylcalix[4]resorcinarene and methoxy-poly(ethylene glycole) (C 5 OPh-mPEG) were described. The conjugate is characterized by 1 H, 13 C NMR, FT-IR, MS, SLS methods. In an aqueous solution the conjugate form multimicellar nanoparticles with low polydispersity value (0.1, DLS method). The self-association of the conjugate was studied by DLS, fluorescence, fluorescence anisotropy method, TEM, and SAXS methods. The SAXS data were detailed analyzed, and the conjugate associates structure as ellipsoidal core-shell particles was proposed. The encapsulation efficiency is a result of the affinity of the conjugate low rim substituents to substrates and reaches of 39.8, 26.7, and 28.9% toward naproxen, ibuprofen and doxorubicin drugs, respectively. | |
dc.relation.ispartofseries | Colloids and Surfaces A: Physicochemical and Engineering Aspects | |
dc.subject | Calix[4]resorcinarene | |
dc.subject | Conjugation | |
dc.subject | Encapsulation | |
dc.subject | PEG | |
dc.subject | SAXS | |
dc.title | The novel calix[4]resorcinarene-PEG conjugate: Synthesis, self-association and encapsulation properties | |
dc.type | Article | |
dc.relation.ispartofseries-volume | 570 | |
dc.collection | Публикации сотрудников КФУ | |
dc.relation.startpage | 182 | |
dc.source.id | SCOPUS09277757-2019-570-SID85062875958 |