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dc.contributor.author | Mostovaya O. | |
dc.contributor.author | Valiullina Y. | |
dc.contributor.author | Chan C. | |
dc.contributor.author | Potrekeeva O. | |
dc.contributor.author | Padnya P. | |
dc.contributor.author | Zuev Y. | |
dc.contributor.author | Stoikov I. | |
dc.date.accessioned | 2020-01-21T20:40:36Z | |
dc.date.available | 2020-01-21T20:40:36Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0959-9436 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/157589 | |
dc.description.abstract | © 2019 A p-tert-butylthiacalix[4]arene derivative containing tryptophan moieties on the lower rim was synthesized and proposed as a chymotrypsin inhibitor. Its ability to competitively inhibit the enzyme was revealed by kinetic methods. A mechanism of the inhibitory action has been established, which consists in the binding of macrocycle tryptophan moieties to the enzyme active site, resulting in its blocking. | |
dc.relation.ispartofseries | Mendeleev Communications | |
dc.title | Synthetic modulator of chymotrypsin activity based on p-tert-butylthiacalix[4]arene | |
dc.type | Article | |
dc.relation.ispartofseries-issue | 5 | |
dc.relation.ispartofseries-volume | 29 | |
dc.collection | Публикации сотрудников КФУ | |
dc.relation.startpage | 520 | |
dc.source.id | SCOPUS09599436-2019-29-5-SID85073758874 |