Synthetic modulator of chymotrypsin activity based on p-tert-butylthiacalix[4]arene

dc.contributor.author	Mostovaya O.
dc.contributor.author	Valiullina Y.
dc.contributor.author	Chan C.
dc.contributor.author	Potrekeeva O.
dc.contributor.author	Padnya P.
dc.contributor.author	Zuev Y.
dc.contributor.author	Stoikov I.
dc.date.accessioned	2020-01-21T20:40:36Z
dc.date.available	2020-01-21T20:40:36Z
dc.date.issued	2019
dc.identifier.issn	0959-9436
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/157589
dc.description.abstract	© 2019 A p-tert-butylthiacalix[4]arene derivative containing tryptophan moieties on the lower rim was synthesized and proposed as a chymotrypsin inhibitor. Its ability to competitively inhibit the enzyme was revealed by kinetic methods. A mechanism of the inhibitory action has been established, which consists in the binding of macrocycle tryptophan moieties to the enzyme active site, resulting in its blocking.
dc.relation.ispartofseries	Mendeleev Communications
dc.title	Synthetic modulator of chymotrypsin activity based on p-tert-butylthiacalix[4]arene
dc.type	Article
dc.relation.ispartofseries-issue	5
dc.relation.ispartofseries-volume	29
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	520
dc.source.id	SCOPUS09599436-2019-29-5-SID85073758874

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.