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Omics of antimicrobials and antimicrobial resistance

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dc.contributor.author Chernov V.
dc.contributor.author Chernova O.
dc.contributor.author Mouzykantov A.
dc.contributor.author Lopukhov L.
dc.contributor.author Aminov R.
dc.date.accessioned 2020-01-15T21:49:51Z
dc.date.available 2020-01-15T21:49:51Z
dc.date.issued 2019
dc.identifier.issn 1746-0441
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/156252
dc.description.abstract © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Introduction: The development of new antimicrobials has become an urgent priority because of a global challenge emerging from the rise of antimicrobial resistant pathogens. Areas covered: In this review, the authors discuss the opportunities offered by modern omics approaches to address the challenge and the use of this approach in antimicrobial development. Specifically, the authors focus on the role of omics technologies and bioinformatics for the revelation of the effects of antimicrobials in a variety of microbial cellular processes, as well as the identification of potential cellular targets, the mechanisms of antimicrobial resistance, and the development of new antimicrobials. Expert opinion: Prevention of antimicrobial resistance does not only depend on rational drug design such as narrow-spectrum antimicrobials but on several factors. It is the opinion of the authors that the use of a multi-omics bioinformatics approach should become an integral part of antimicrobial drug discovery as well as in the prevention of antimicrobial resistance.
dc.relation.ispartofseries Expert Opinion on Drug Discovery
dc.subject antimicrobial resistance mechanisms
dc.subject Antimicrobials
dc.subject genomics
dc.subject metabolomics
dc.subject novel antimicrobials
dc.subject proteomics
dc.subject transcriptomics
dc.title Omics of antimicrobials and antimicrobial resistance
dc.type Review
dc.relation.ispartofseries-issue 5
dc.relation.ispartofseries-volume 14
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 455
dc.source.id SCOPUS17460441-2019-14-5-SID85064348968


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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