Isolation, characterization and antibiotic activities of new variants of actinomycetes

Abstract

Copyright © 2019 American Scientific Publishers. All rights reserved. In order to find new antibiotics the investigation was undertaken and resulted in isolation of 18 actinomycetes from different samples of soils of Mongolia, and different types of Russia soil and the waste water. Out of 18 isolates 9 showed inhibitory activity against at least one of four bacteria i.e., Bacillus megaterium, Salmonella typhimurium, Listeria monocytogenes, or Pseudomonas putida, and 6 of the 18—against at least one of five fungi, i.e., Trichoderma asperellum, Aspergillus Niger, Penicillus sp., Fusarium oxysporum, or Saccharomyces cerevisiae. The isolates, inhibiting the growth of bacteria and fungi, were identified on the bases of morphological and biochemical properties as well as 16S rDNA sequence analysis. Further works are needed on optimization of these isolates’ antagonistic activities and characterization of the antimicrobial metabolites.