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Performance of the Enferplex TB assay with cattle in Great Britain and assessment of its suitability as a test to distinguish infected and vaccinated animals

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dc.contributor Казанский федеральный университет
dc.contributor.author Whelan Clare
dc.contributor.author Whelan Adam O.
dc.contributor.author Shuralev Eduard Arkadevich
dc.contributor.author Kwok Hang Fai
dc.contributor.author Hewinson Glyn
dc.contributor.author Clarke John
dc.contributor.author Vordermeier H. Martin
dc.date.accessioned 2019-02-12T11:01:23Z
dc.date.available 2019-02-12T11:01:23Z
dc.date.issued 2010
dc.identifier.citation Whelan C. Performance of the Enferplex TB assay with cattle in Great Britain and assessment of its suitability as a test to distinguish infected and vaccinated animals / C. Whelan, A.O. Whelan, E. Shuralev, H.F. Kwok, G. Hewinson, J. Clarke, H.M. Vordermeier // Clin Vaccine Immunol. - 2010. -Vol.17. - No. 5: 813-817. DOI: 10.1128/CVI.00489-09
dc.identifier.issn 1556-6811
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/149793
dc.description.abstract Our results indicate that the test has a relative sensitivity range of 77.0% to 86.5% at corresponding specificity levels of 100.0% to 77.6%. Comparison with the Bovigam gamma interferon antemortem test revealed that this serology test was significantly more sensitive at specificities above 97.9%, while the Bovigam test was, on average, about 10% more sensitive when the test specificity was set below 97%. Importantly, this serological multiplex assay does not react with sera from BCG-vaccinated calves and is therefore suitable as a DIVA test alongside BCG-based vaccine strategies.
dc.language.iso en
dc.relation.ispartofseries CLIN VACCINE IMMUNOL
dc.rights открытый доступ
dc.subject Mycobacterium bovis
dc.subject BCG
dc.subject cattle
dc.subject Bovigam
dc.subject gamma interferon
dc.subject vaccination
dc.subject multiplex
dc.subject immunoassay
dc.subject.other Биология
dc.subject.other Медицина и здравоохранение
dc.subject.other Сельское и лесное хозяйство
dc.title Performance of the Enferplex TB assay with cattle in Great Britain and assessment of its suitability as a test to distinguish infected and vaccinated animals
dc.type Article
dc.contributor.org Институт экологии и природопользования
dc.description.pages
dc.relation.ispartofseries-issue 5
dc.relation.ispartofseries-volume 17
dc.pub-id 35749


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