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Influence of Standardized Extract Ginkgo biloba EGb761<sup>®</sup> Towards Quality of Life Indicators in Patients with Diabetes Mellitus Type 2

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dc.contributor.author Esin R.
dc.contributor.author Esin O.
dc.contributor.author Khayrullin I.
dc.date.accessioned 2019-01-22T20:57:32Z
dc.date.available 2019-01-22T20:57:32Z
dc.date.issued 2018
dc.identifier.issn 2191-1630
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/149615
dc.description.abstract © 2018, Springer Science+Business Media, LLC, part of Springer Nature. Cognitive impairment in patients with type 2 diabetes mellitus (DM-2) currently attracts a lot of attention due to their impact on quality of life and the effectiveness of treatment. The aim of research is to find the most effective medication which influences the cognitive functions positively. The research included 120 patients with average age of 61.22 ± 8.6 and average DM-2 duration of 10.84 ± 8.2 years. Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA test), Trail Making Test (TMT), Parts A and B, Hospital Anxiety and Depression Scale (HADS), and The Short Form-36 (SF-36) were used. It was revealed that patients with DM type 2 had cognitive dysfunction generally presented by mild cognitive impairment. Patients with DM-2 have an early manifestation of cognitive impairment. After the initial estimation of indicators, all the patients were taking standardized extract Ginkgo biloba (EGb 761®) in the dose 240 mg a day for 6 months. Estimation of all the indicators after 3 and 6 months of treatment showed significant cognitive improvement. By matching the available experimental and clinical data, we can conclude that in the setting of DM-2 EGb 761®, by producing a positive effect towards various factors which results from insulin resistance of the brain, improves functions of the brain, which manifests in improvement of main QoL indicators in DM-2.
dc.relation.ispartofseries BioNanoScience
dc.subject Cognitive decline
dc.subject Diabetes mellitus type 2
dc.subject EGb 761
dc.subject Neurocognitive tests
dc.subject Quality of life
dc.title Influence of Standardized Extract Ginkgo biloba EGb761<sup>®</sup> Towards Quality of Life Indicators in Patients with Diabetes Mellitus Type 2
dc.type Article
dc.relation.ispartofseries-issue 3
dc.relation.ispartofseries-volume 8
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 916
dc.source.id SCOPUS21911630-2018-8-3-SID85052821588


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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