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Antibiotic Susceptibility Assessment of Helicobacter pylori Isolates by Disk-Diffusion Method

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dc.contributor.author Akhtereeva A.
dc.contributor.author Morozova L.
dc.contributor.author Faizullina R.
dc.contributor.author Ivanovskaya K.
dc.contributor.author Pozdeev O.
dc.contributor.author Valeeva I.
dc.contributor.author Abdulkhakov S.
dc.date.accessioned 2019-01-22T20:57:29Z
dc.date.available 2019-01-22T20:57:29Z
dc.date.issued 2018
dc.identifier.issn 2191-1630
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/149610
dc.description.abstract © 2018, Springer Science+Business Media, LLC, part of Springer Nature. Helicobacter pylori (H. pylori) infection is tightly associated with gastrointestinal disorders such as chronic gastritis, peptic ulcer, gastric MALToma, and gastric cancer. Decreased antibiotic susceptibility in H. pylori is a worldwide problem. Our objective was to determine in vitro antimicrobial susceptibility of H. pylori isolates obtained from gastric mucosa biopsies of children with H. pylori-associated gastroduodenal diseases using disk-diffusion method. A total 76 biopsy specimens were studied; antibiotic susceptibility was assessed in case of 30 children in whom H. pylori was revealed by bacteriology. The maximum resistance of H. pylori isolates was revealed to clarithromycin with nine resistant isolates (30.0%). The rate of resistance to metronidazole, amoxicillin, furazolidone, tetracycline, and levofloxacin was 23.3, 33.3, 16.7, 25.0, and 16.7%, respectively. Multidrug resistance was detected in 20.0% of H. pylori strains. The high prevalence of resistance to antibiotics used in eradication therapy is becoming a problem which needs eradication therapy regimen use based on regional H. pylori resistance rates.
dc.relation.ispartofseries BioNanoScience
dc.subject Antibiotic susceptibility
dc.subject Children
dc.subject Disk-diffusion method
dc.subject Helicobacter pylori
dc.title Antibiotic Susceptibility Assessment of Helicobacter pylori Isolates by Disk-Diffusion Method
dc.type Article
dc.relation.ispartofseries-issue 3
dc.relation.ispartofseries-volume 8
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 930
dc.source.id SCOPUS21911630-2018-8-3-SID85052740148


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  • Публикации сотрудников КФУ Scopus [22633]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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