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The stromal vascular fraction from fat tissue in the treatment of osteochondral knee defect: Case report

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dc.contributor.author Teplov O.
dc.contributor.author Galimov D.
dc.contributor.author Plakseichuk Y.
dc.contributor.author Yagudin R.
dc.contributor.author Pankov I.
dc.contributor.author Rizvanov A.
dc.date.accessioned 2019-01-22T20:54:09Z
dc.date.available 2019-01-22T20:54:09Z
dc.date.issued 2018
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/149338
dc.description.abstract © 2018 Salikhov, Masgutov, Chekunov, Tazetdinova, Masgutova, Teplov, Galimov, Plakseichuk, Yagudin, Pankov and Rizvanov. In this study we applied autologous fat tissue stromal vascular fraction (SVF) cells in combination with microfracturing technique in a 36-year-old man with an osteochondral lesion of the medial femoral condyle 8 months after the injury. Cell material was generated by fat tissue liposuction from the anterior abdominal wall with subsequent extraction of the SVF and injected through a mini-arthrotomy portal with subsequent fibrin sealant fixation. The follow-up period was 2 years. Clinical score improved from 23 to 96 according to IKDC and from 10 to 90 according to EQ-VAS at 24 months follow-up. Magnetic resonance imaging (MRI) before the surgery revealed an osteochondral lesion with development of significant trabecular edema that remained unchanged for 6 months despite conservative treatment. MRI 1 and 2 years after the surgery showed the recovery of the damaged cartilage thickness with somewhat uneven structure and a decrease in the trabecular edema of the femoral condyle. The use of SVF cells with fibrin sealant fixation might be a promising approach in the treatment of osteochondral joint lesions. Further studies are required.
dc.subject Fat tissue
dc.subject Fibrin sealant
dc.subject Mesenchymal stem cells
dc.subject Osteochondral lesions of the knee
dc.subject Stromal vascular fraction
dc.title The stromal vascular fraction from fat tissue in the treatment of osteochondral knee defect: Case report
dc.type Article
dc.relation.ispartofseries-issue MAY
dc.relation.ispartofseries-volume 5
dc.collection Публикации сотрудников КФУ
dc.source.id SCOPUS-2018-5--SID85050162921

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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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