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dc.date.accessioned | 2019-01-22T20:53:47Z | |
dc.date.available | 2019-01-22T20:53:47Z | |
dc.date.issued | 2018 | |
dc.identifier.uri | https://dspace.kpfu.ru/xmlui/handle/net/149315 | |
dc.description.abstract | © 2018 by the authors The tetracyclic pyrido[4,3-b]carbazole olivacine and four of its oxygenated derivatives have been synthesized by a late-stage palladium-catalyzed Heck-type cyclization of the pyrrole ring as a key step. In a test for the inhibition of the growth of Mycobacterium tuberculosis, 9-methoxyolivacine showed the most significant inhibitory activity against Mycobacterium tuberculosis, with an MIC90 value of 1.5 µM. | |
dc.subject | 3-b]carbazoles | |
dc.subject | Catalysis | |
dc.subject | Cyclization | |
dc.subject | Inhibitory activity | |
dc.subject | Olivacine | |
dc.subject | Palladium | |
dc.subject | Pyrido[4 | |
dc.title | Synthesis and activity against mycobacterium tuberculosis of olivacine and oxygenated derivatives | |
dc.type | Article | |
dc.relation.ispartofseries-issue | 6 | |
dc.relation.ispartofseries-volume | 23 | |
dc.collection | Публикации сотрудников КФУ | |
dc.source.id | SCOPUS-2018-23-6-SID85048326877 |