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5-Amino-Substituted Derivatives of 4-Nitrofurazane: Synthesis, Structure, and Biological Activity

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dc.contributor.author Islamov D.
dc.contributor.author Bakhtiyarova Y.
dc.contributor.author Yamalieva L.
dc.contributor.author Kataeva O.
dc.contributor.author Galkin V.
dc.date.accessioned 2019-01-22T20:42:16Z
dc.date.available 2019-01-22T20:42:16Z
dc.date.issued 2018
dc.identifier.issn 1070-3632
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/148361
dc.description.abstract © 2018, Pleiades Publishing, Ltd. New amination reactions of 5-chloro-4-nitrobenzofurazane with different amines were studied. The reactions of 5-chloro-4-nitrobenzofurazane with 2,4,6-trichloro-, para-acetyl-, and para-carboxyethylanilines gave the products of aromatic nucleophilic substitution of the chlorine substituent in the nitrogenous heterocycle, the composition and structure of which was established by chemical, physical, and physicochemical methods and X-ray diffraction analysis. The thermal stability was studied by synchronous thermogravimetry and differential scanning calorimetry (TG‒DSC). The synthesized compounds showed a high antibacterial and antimycotic activity against human and animal pathogenic microflora.
dc.relation.ispartofseries Russian Journal of General Chemistry
dc.subject 5-chloro-4-nitrobenzofurazane
dc.subject heterocyclic compounds
dc.subject nucleophilic aromatic substitution
dc.subject substituted anilines
dc.title 5-Amino-Substituted Derivatives of 4-Nitrofurazane: Synthesis, Structure, and Biological Activity
dc.type Article
dc.relation.ispartofseries-issue 5
dc.relation.ispartofseries-volume 88
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 898
dc.source.id SCOPUS10703632-2018-88-5-SID85049322088


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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