dc.date.accessioned |
2019-01-22T20:32:19Z |
|
dc.date.available |
2019-01-22T20:32:19Z |
|
dc.date.issued |
2018 |
|
dc.identifier.issn |
0013-4686 |
|
dc.identifier.uri |
https://dspace.kpfu.ru/xmlui/handle/net/147613 |
|
dc.description.abstract |
© 2018 Elsevier Ltd Novel electrochemical sensor based on poly(p-coumaric acid) electrodeposited on the surface of multi-walled carbon nanotubes modified glassy carbon electrode (poly(p-coumaric acid)/MWNT/GCE) has been developed for the direct determination of L-cysteine. Poly(p-coumaric acid) has been obtained by potentiodynamic electrolysis under the optimized conditions (0.10 mM p-coumaric acid in 0.1 M NaOH using 5 cycles in the potential window of 0–1.0 V and the scan rate of 25 mV s−1) providing highest voltammetric response of L-cysteine. Sensor surface has been studied by scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The porous structure of polymeric film provides 6.9-fold increase in effective surface area and 4.2-fold lower charge transfer resistance in comparison to GCE. Under conditions of DPV, the sensor response is linear in the ranges of 7.5–50 and 50–1000 μM of L-cysteine with the detection and quantification limits of 1.1 and 3.6 μM, respectively. The excellent sensor selectivity to L-cysteine in the presence of glucose, uric and ascorbic acids, dopamine, L-tyrosine and S-containing substances (homocysteine, glutathione, L-methionine, L-cystine and α-lipoic acid) has been observed. Applicability of the sensor to real samples analysis has been shown on example of human urine. |
|
dc.relation.ispartofseries |
Electrochimica Acta |
|
dc.subject |
Electrochemical sensors |
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dc.subject |
Electropolymerization |
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dc.subject |
L-cysteine |
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dc.subject |
p-Coumaric acid |
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dc.subject |
Voltammetry |
|
dc.title |
Selective electrochemical sensor based on the electropolymerized p-coumaric acid for the direct determination of L-cysteine |
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dc.type |
Article |
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dc.relation.ispartofseries-volume |
270 |
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dc.collection |
Публикации сотрудников КФУ |
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dc.relation.startpage |
369 |
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dc.source.id |
SCOPUS00134686-2018-270-SID85044144988 |
|