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Evaluation of the Influence of Antifungal Drugs on Growth of Candida albicans in the Biofilm

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dc.contributor.author Lisovskaya S.
dc.contributor.author Khaldeeva E.
dc.contributor.author Salmakova A.
dc.contributor.author Kulikov S.
dc.date.accessioned 2018-09-19T23:11:27Z
dc.date.available 2018-09-19T23:11:27Z
dc.date.issued 2016
dc.identifier.issn 2191-1630
dc.identifier.uri https://dspace.kpfu.ru/xmlui/handle/net/146033
dc.description.abstract © 2016, Springer Science+Business Media New York.The influence of commonly used in clinical practice, antifungals (fluconazole, voriconazole, nystatin, terbinafine), on Candida albicans cell cultures was investigated. Clinical strains isolated from patients with clinical signs of superficial candidal infections of various localizations were tested. Sensitivity of strains to drugs on planktonic cells and in the biofilms was determined. Strains with various levels of sensitivity and resistant to antimycotics were identified. It was established that MICs of the antifungal drugs which inhibit the growth of the biofilms were up to 1000 times higher than MICs, inhibiting growth of planktonic cells.
dc.relation.ispartofseries BioNanoScience
dc.subject Antifungal activity
dc.subject Biofilm
dc.subject Candida albicans
dc.subject Minimal inhibitory concentration
dc.title Evaluation of the Influence of Antifungal Drugs on Growth of Candida albicans in the Biofilm
dc.type Article
dc.relation.ispartofseries-issue 4
dc.relation.ispartofseries-volume 6
dc.collection Публикации сотрудников КФУ
dc.relation.startpage 588
dc.source.id SCOPUS21911630-2016-6-4-SID84999752007


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  • Публикации сотрудников КФУ Scopus [24551]
    Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.

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