Peculiar Aspects in Influence of α1-Adrenoceptor Stimulation on Isolated Rat Heart

dc.contributor.author	Zefirov T.
dc.contributor.author	Khabibrakhmanov I.
dc.contributor.author	Ziyatdinova N.
dc.contributor.author	Zefirov A.
dc.date.accessioned	2018-09-19T22:18:18Z
dc.date.available	2018-09-19T22:18:18Z
dc.date.issued	2016
dc.identifier.uri	https://dspace.kpfu.ru/xmlui/handle/net/144992
dc.description.abstract	The study examined the effect of α1-adrenoceptor stimulation with methoxamine on chronotropic function of isolated heart perfused ex vivo according to Langendorff and cardiac chronotropy in vivo. Stimulation of α1-adrenoceptors in isolated heart induced gradually developing bradycardia, which progressed during several minutes. Similar stimulation in vivo produced a short-term bradycardia probably terminated by the compensatory influences in the whole organism. Comparison of the data obtained in both experimental paradigms during α1-adrenoceptor stimulation revealed unidirectional changes in cardiac chronotropy characterized with time-related peculiarities.
dc.subject	chronotropy
dc.subject	heart
dc.subject	methoxamine
dc.subject	rat
dc.subject	α1-adrenoceptor
dc.title	Peculiar Aspects in Influence of α1-Adrenoceptor Stimulation on Isolated Rat Heart
dc.type	Article
dc.relation.ispartofseries-issue	1
dc.relation.ispartofseries-volume	162
dc.collection	Публикации сотрудников КФУ
dc.relation.startpage	4
dc.source.id	SCOPUS-2016-162-1-SID85011945211

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Публикации сотрудников КФУ Scopus [24551]
Коллекция содержит публикации сотрудников Казанского федерального (до 2010 года Казанского государственного) университета, проиндексированные в БД Scopus, начиная с 1970г.